Sickle cell disease clinical trials
185 studies are looking for volunteers right now. Search near you to see which are close by and who can take part.
Or see all sickle cell disease studies in TrialFinder. Live data from ClinicalTrials.gov, updated daily.
At a glance
Where the studies are
U.S. states with the most recruiting sickle cell disease studies. A study counts once in each state where it has a site.
- Tennessee25
- New York24
- Ohio24
- Georgia23
- Pennsylvania23
- Maryland22
- California21
- North Carolina21
- Alabama19
- Illinois19
- Texas17
- District of Columbia14
Also in France (29), United Kingdom (12), Canada (9), Nigeria (9), Italy (8), Spain (8), Belgium (7), Germany (7).
Types of study
Phases 1 to 4 test medicines, from first safety checks to long-term follow-up after approval. Trials of devices and programs have no phase. Observational studies give no study treatment.
- Early phase 12
- Phase 112
- Phase 1 / Phase 216
- Phase 228
- Phase 2 / Phase 32
- Phase 311
- Phase 45
- No phase (devices, programs)51
- Observational58
Recently updated studies
Recruiting sickle cell disease studies whose listing changed most recently. Open one in TrialFinder to check if you might qualify.
- RecruitingPhase 1 / Phase 2NCT06546670
A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease
Ages 12 Years – 55 Years · Birmingham, Alabama · Miami, Florida +12 more · Novartis Pharmaceuticals
- RecruitingObservationalNCT03685721
Genotype -Phenotype Correlation of PKLR Variants With Pyruvate Kinase, 2,3-Diphosphglycerate and Adenosine Triphosphate Activities in Red Blood Cells of People With Sickle Cell Disease
Ages 18 Years – 80 Years · Bethesda, Maryland · National Heart, Lung, and Blood Institute (NHLBI)
- RecruitingObservationalNCT07543289
Hydroxyurea Optimisation in Sickle Cell Disease
Ages 18 Years and over · Ile-Ife, Osun State · Ochuko Orherhe
- RecruitingObservationalNCT00542230
Blood Sampling for Research Related to Sickle Cell Disease
Ages 18 Years – 100 Years · Bethesda, Maryland · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- RecruitingPhase 1 / Phase 2NCT04008368
Repeat Peripheral Blood Stem Cell Transplantation for Patients With Sickle Cell Disease and Falling Donor Myeloid Chimerism Levels
Ages 2 Years – 80 Years · Bethesda, Maryland · National Heart, Lung, and Blood Institute (NHLBI)
- RecruitingPhase 2NCT04099966
AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion
Ages 1 Day – 30 Years · Valhalla, New York · Mitchell Cairo
- RecruitingNo phase (devices, programs)NCT07090668
Trans-auricular Nerve Stimulation as an Innovative Approach to the Treatment of Pain in Pediatric Patients Suffering From Sickle Cell Disease
Ages 7 Years – 18 Years · Atlanta, Georgia · Emory University
- RecruitingObservationalNCT05213572
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
Ages 18 Years – 100 Years · Bethesda, Maryland · National Heart, Lung, and Blood Institute (NHLBI)
Worth knowing
- Taking part is your choice, and you can stop at any time.
- Each study has rules about who can join. The study team checks them with you before you start.
- Talk to your doctor about whether a study is a good fit for you.